GDF3 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | Q9NR23 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | ecat9; GDF3; KFS3; MCOP7; Vgr2; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 41387 Da |
Dilution | WB 1:500~1:2000 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human GDF3 |
Description | Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor TDGF1/Cripto (By similarity). |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | GDF3 |
---|---|
Function | Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor CRIPTO (By similarity). Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and CRIPTO/Cripto (PubMed:21805089). |
Cellular Location | Secreted. Cytoplasm. Note=Mainly accumulated in the cytoplasm |

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